Pythion
Last Updated: June 4, 2025
Pythion Overview
Legends long told of Duchess Lilitu as the most dominant Arena champion for years, but in 2023 a new challenger emerged. Pythion joined the Lizardmen faction as the January 2023 Fragment Fusion champion, and at the time, it is no exaggeration to call him the best fusion ever released since fusions began in 2019.
Pythion’s kit is focused on protecting and carrying his team. His A3 provides a full team revive, bringing allies back with 50% HP and Turn Meter, while also placing a 25% Strengthen buff on all allies. This ability only activates once an ally has fallen, making it strong in Arena Defense and generally. His A2 offers a 3 turn cooldown, AoE full debuff cleanse followed by a heal equal to 10% of allies’ MAX HP, increased by 5% for each debuff removed, before placing Block Debuffs for two turns. This is an incredibly powerful tool for handling heavy debuff teams & bosses.
What truly elevates Pythion is his passive, which reduces incoming damage to the team by 5% for each buff on allies, stacking up to 25%. This mirrors the strength of Duchess Lilitu’s passive and provides massive damage mitigation, making Pythion an outstanding defensive cornerstone for virtually any team in the game.
Pythion Ratings
Pythion Skills

10/10
Book Value
Book Priority
Pythion PVE Masteries




![Shield Breaker - Increases damage inflicted to targets under [Shield], buffs by 25% shield-breaker](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/shield-breaker.png)








![Opportunist - Increases damage inflicted to targets with [Stun], [Sleep], [Fear], [True Fear], [Freeze], [Petrification], debuffs by 12%. opportunist](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/opportunist.png)


![Blood Shield - Places a [Shield], buff on this Champion for 1 turn when this Champion kills an enemy. The value of the [Shield], is equal to 15% of this Champion's MAX HP. Occurs once per turn blood-shield](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/blood-shield.png)








![Rejuvenation - Increases the amount of healing and the value of [Shield], buffs this Champion receives by 5% rejuvenation](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/rejuvenation.png)
![Mighty Endurance - Decreases the damage received by 10% if this Champion has [Stun], [Sleep], [Fear], [True Fear], [Freeze], [Petrification], debuffs. might-endurance](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/might-endurance.png)




![Wisdom of Battle - Has a 30% chance of placing a [Block Debuffs], buff on this Champion for 1 turn when [Stun], [Sleep], [Fear], [True Fear], [Freeze], [Petrification], debuffs expire on this Champion. wisdom-of-battle](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/wisdom-of-battle.png)


![Harvest Despair - Has a 60% chance of placing a [Leech], debuff for 1 turn when placing [Stun], [Sleep], [Fear], [True Fear], [Freeze], [Petrification], debuffs. harvest-despair](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/harvest-despair.png)




![Deterrence - Has a 20% chance to counterattack an enemy when they apply a [Stun], [Sleep], [Fear], [True Fear], [Freeze], [Petrification], debuff on an ally. Cooldown: 1 turn deterrence](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/deterrence.png)


![Fearsome Presence - Increases the chances of placing a [Stun], [Sleep], [Freeze], [Fear], [True Fear], [Provoke], or [Sheep], debuff from Skills or Artifacts by 5% fearsome-presence](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/fearsome-presence.png)




![Shieldbearer - Increases the value of [Shield], buffs this Champion casts by 5% shieldbearer](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/shieldbearer.png)


![Healing Savior - Increases the amount of healing and the value of [Shield], buffs placed by this Champion by 10% if the target ally has 40% HP or less healing-savior](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/healing-savior.png)



![Merciful Aid - Increases the amount of healing and the value of [Shield], buffs placed by this Champion by 15% if the target ally has [Stun], [Sleep], [Fear], [True Fear], or [Freeze] debuffs merciful-aid](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/merciful-aid.png)



![Lasting Gifts - Has a 30% chance to extend the duration of any buff cast by this Champion by 1 turn.
It will not extend [Block Damage], [Unkillable], or [Revive on Death], buffs. lasting-gifts](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/lasting-gifts.png)

![Sniper - Increases the chances of placing any debuff from Skills or Artifacts by 5%.
It will not increase the chances of placing [Stun], [Sleep], [Freeze], [Fear], [True Fear], [Provoke], or [Petrification], debuffs. sniper](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/sniper.png)
![Master Hexer - Has a 30% chance to extend the duration of any debuff cast by this Champion by 1 turn. It will not extend [Stun], [Sleep], [Freeze], [Provoke], [Fear], [True Fear], [Bomb], or [Petrification], debuffs. master-hexer](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/master-hexer.png)








![Shield Breaker - Increases damage inflicted to targets under [Shield], buffs by 25% shield-breaker](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/shield-breaker.png)








![Opportunist - Increases damage inflicted to targets with [Stun], [Sleep], [Fear], [True Fear], [Freeze], [Petrification], debuffs by 12%. opportunist](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/opportunist.png)


![Blood Shield - Places a [Shield], buff on this Champion for 1 turn when this Champion kills an enemy. The value of the [Shield], is equal to 15% of this Champion's MAX HP. Occurs once per turn blood-shield](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/blood-shield.png)








![Rejuvenation - Increases the amount of healing and the value of [Shield], buffs this Champion receives by 5% rejuvenation](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/rejuvenation.png)
![Mighty Endurance - Decreases the damage received by 10% if this Champion has [Stun], [Sleep], [Fear], [True Fear], [Freeze], [Petrification], debuffs. might-endurance](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/might-endurance.png)




![Wisdom of Battle - Has a 30% chance of placing a [Block Debuffs], buff on this Champion for 1 turn when [Stun], [Sleep], [Fear], [True Fear], [Freeze], [Petrification], debuffs expire on this Champion. wisdom-of-battle](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/wisdom-of-battle.png)


![Harvest Despair - Has a 60% chance of placing a [Leech], debuff for 1 turn when placing [Stun], [Sleep], [Fear], [True Fear], [Freeze], [Petrification], debuffs. harvest-despair](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/harvest-despair.png)




![Deterrence - Has a 20% chance to counterattack an enemy when they apply a [Stun], [Sleep], [Fear], [True Fear], [Freeze], [Petrification], debuff on an ally. Cooldown: 1 turn deterrence](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/deterrence.png)


![Fearsome Presence - Increases the chances of placing a [Stun], [Sleep], [Freeze], [Fear], [True Fear], [Provoke], or [Sheep], debuff from Skills or Artifacts by 5% fearsome-presence](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/fearsome-presence.png)




![Shieldbearer - Increases the value of [Shield], buffs this Champion casts by 5% shieldbearer](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/shieldbearer.png)


![Healing Savior - Increases the amount of healing and the value of [Shield], buffs placed by this Champion by 10% if the target ally has 40% HP or less healing-savior](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/healing-savior.png)



![Merciful Aid - Increases the amount of healing and the value of [Shield], buffs placed by this Champion by 15% if the target ally has [Stun], [Sleep], [Fear], [True Fear], or [Freeze] debuffs merciful-aid](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/merciful-aid.png)



![Lasting Gifts - Has a 30% chance to extend the duration of any buff cast by this Champion by 1 turn.
It will not extend [Block Damage], [Unkillable], or [Revive on Death], buffs. lasting-gifts](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/lasting-gifts.png)

![Sniper - Increases the chances of placing any debuff from Skills or Artifacts by 5%.
It will not increase the chances of placing [Stun], [Sleep], [Freeze], [Fear], [True Fear], [Provoke], or [Petrification], debuffs. sniper](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/sniper.png)
![Master Hexer - Has a 30% chance to extend the duration of any debuff cast by this Champion by 1 turn. It will not extend [Stun], [Sleep], [Freeze], [Provoke], [Fear], [True Fear], [Bomb], or [Petrification], debuffs. master-hexer](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/master-hexer.png)








![Shield Breaker - Increases damage inflicted to targets under [Shield], buffs by 25% shield-breaker](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/shield-breaker.png)








![Opportunist - Increases damage inflicted to targets with [Stun], [Sleep], [Fear], [True Fear], [Freeze], [Petrification], debuffs by 12%. opportunist](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/opportunist.png)


![Blood Shield - Places a [Shield], buff on this Champion for 1 turn when this Champion kills an enemy. The value of the [Shield], is equal to 15% of this Champion's MAX HP. Occurs once per turn blood-shield](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/blood-shield.png)








![Rejuvenation - Increases the amount of healing and the value of [Shield], buffs this Champion receives by 5% rejuvenation](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/rejuvenation.png)
![Mighty Endurance - Decreases the damage received by 10% if this Champion has [Stun], [Sleep], [Fear], [True Fear], [Freeze], [Petrification], debuffs. might-endurance](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/might-endurance.png)




![Wisdom of Battle - Has a 30% chance of placing a [Block Debuffs], buff on this Champion for 1 turn when [Stun], [Sleep], [Fear], [True Fear], [Freeze], [Petrification], debuffs expire on this Champion. wisdom-of-battle](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/wisdom-of-battle.png)


![Harvest Despair - Has a 60% chance of placing a [Leech], debuff for 1 turn when placing [Stun], [Sleep], [Fear], [True Fear], [Freeze], [Petrification], debuffs. harvest-despair](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/harvest-despair.png)




![Deterrence - Has a 20% chance to counterattack an enemy when they apply a [Stun], [Sleep], [Fear], [True Fear], [Freeze], [Petrification], debuff on an ally. Cooldown: 1 turn deterrence](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/deterrence.png)


![Fearsome Presence - Increases the chances of placing a [Stun], [Sleep], [Freeze], [Fear], [True Fear], [Provoke], or [Sheep], debuff from Skills or Artifacts by 5% fearsome-presence](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/fearsome-presence.png)




![Shieldbearer - Increases the value of [Shield], buffs this Champion casts by 5% shieldbearer](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/shieldbearer.png)


![Healing Savior - Increases the amount of healing and the value of [Shield], buffs placed by this Champion by 10% if the target ally has 40% HP or less healing-savior](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/healing-savior.png)



![Merciful Aid - Increases the amount of healing and the value of [Shield], buffs placed by this Champion by 15% if the target ally has [Stun], [Sleep], [Fear], [True Fear], or [Freeze] debuffs merciful-aid](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/merciful-aid.png)



![Lasting Gifts - Has a 30% chance to extend the duration of any buff cast by this Champion by 1 turn.
It will not extend [Block Damage], [Unkillable], or [Revive on Death], buffs. lasting-gifts](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/lasting-gifts.png)

![Sniper - Increases the chances of placing any debuff from Skills or Artifacts by 5%.
It will not increase the chances of placing [Stun], [Sleep], [Freeze], [Fear], [True Fear], [Provoke], or [Petrification], debuffs. sniper](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/sniper.png)
![Master Hexer - Has a 30% chance to extend the duration of any debuff cast by this Champion by 1 turn. It will not extend [Stun], [Sleep], [Freeze], [Provoke], [Fear], [True Fear], [Bomb], or [Petrification], debuffs. master-hexer](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/master-hexer.png)




Pythion PVP Masteries




![Shield Breaker - Increases damage inflicted to targets under [Shield], buffs by 25% shield-breaker](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/shield-breaker.png)








![Opportunist - Increases damage inflicted to targets with [Stun], [Sleep], [Fear], [True Fear], [Freeze], [Petrification], debuffs by 12%. opportunist](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/opportunist.png)


![Blood Shield - Places a [Shield], buff on this Champion for 1 turn when this Champion kills an enemy. The value of the [Shield], is equal to 15% of this Champion's MAX HP. Occurs once per turn blood-shield](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/blood-shield.png)








![Rejuvenation - Increases the amount of healing and the value of [Shield], buffs this Champion receives by 5% rejuvenation](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/rejuvenation.png)
![Mighty Endurance - Decreases the damage received by 10% if this Champion has [Stun], [Sleep], [Fear], [True Fear], [Freeze], [Petrification], debuffs. might-endurance](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/might-endurance.png)




![Wisdom of Battle - Has a 30% chance of placing a [Block Debuffs], buff on this Champion for 1 turn when [Stun], [Sleep], [Fear], [True Fear], [Freeze], [Petrification], debuffs expire on this Champion. wisdom-of-battle](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/wisdom-of-battle.png)


![Harvest Despair - Has a 60% chance of placing a [Leech], debuff for 1 turn when placing [Stun], [Sleep], [Fear], [True Fear], [Freeze], [Petrification], debuffs. harvest-despair](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/harvest-despair.png)




![Deterrence - Has a 20% chance to counterattack an enemy when they apply a [Stun], [Sleep], [Fear], [True Fear], [Freeze], [Petrification], debuff on an ally. Cooldown: 1 turn deterrence](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/deterrence.png)


![Fearsome Presence - Increases the chances of placing a [Stun], [Sleep], [Freeze], [Fear], [True Fear], [Provoke], or [Sheep], debuff from Skills or Artifacts by 5% fearsome-presence](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/fearsome-presence.png)




![Shieldbearer - Increases the value of [Shield], buffs this Champion casts by 5% shieldbearer](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/shieldbearer.png)


![Healing Savior - Increases the amount of healing and the value of [Shield], buffs placed by this Champion by 10% if the target ally has 40% HP or less healing-savior](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/healing-savior.png)



![Merciful Aid - Increases the amount of healing and the value of [Shield], buffs placed by this Champion by 15% if the target ally has [Stun], [Sleep], [Fear], [True Fear], or [Freeze] debuffs merciful-aid](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/merciful-aid.png)



![Lasting Gifts - Has a 30% chance to extend the duration of any buff cast by this Champion by 1 turn.
It will not extend [Block Damage], [Unkillable], or [Revive on Death], buffs. lasting-gifts](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/lasting-gifts.png)

![Sniper - Increases the chances of placing any debuff from Skills or Artifacts by 5%.
It will not increase the chances of placing [Stun], [Sleep], [Freeze], [Fear], [True Fear], [Provoke], or [Petrification], debuffs. sniper](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/sniper.png)
![Master Hexer - Has a 30% chance to extend the duration of any debuff cast by this Champion by 1 turn. It will not extend [Stun], [Sleep], [Freeze], [Provoke], [Fear], [True Fear], [Bomb], or [Petrification], debuffs. master-hexer](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/master-hexer.png)








![Shield Breaker - Increases damage inflicted to targets under [Shield], buffs by 25% shield-breaker](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/shield-breaker.png)








![Opportunist - Increases damage inflicted to targets with [Stun], [Sleep], [Fear], [True Fear], [Freeze], [Petrification], debuffs by 12%. opportunist](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/opportunist.png)


![Blood Shield - Places a [Shield], buff on this Champion for 1 turn when this Champion kills an enemy. The value of the [Shield], is equal to 15% of this Champion's MAX HP. Occurs once per turn blood-shield](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/blood-shield.png)








![Rejuvenation - Increases the amount of healing and the value of [Shield], buffs this Champion receives by 5% rejuvenation](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/rejuvenation.png)
![Mighty Endurance - Decreases the damage received by 10% if this Champion has [Stun], [Sleep], [Fear], [True Fear], [Freeze], [Petrification], debuffs. might-endurance](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/might-endurance.png)




![Wisdom of Battle - Has a 30% chance of placing a [Block Debuffs], buff on this Champion for 1 turn when [Stun], [Sleep], [Fear], [True Fear], [Freeze], [Petrification], debuffs expire on this Champion. wisdom-of-battle](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/wisdom-of-battle.png)


![Harvest Despair - Has a 60% chance of placing a [Leech], debuff for 1 turn when placing [Stun], [Sleep], [Fear], [True Fear], [Freeze], [Petrification], debuffs. harvest-despair](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/harvest-despair.png)




![Deterrence - Has a 20% chance to counterattack an enemy when they apply a [Stun], [Sleep], [Fear], [True Fear], [Freeze], [Petrification], debuff on an ally. Cooldown: 1 turn deterrence](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/deterrence.png)


![Fearsome Presence - Increases the chances of placing a [Stun], [Sleep], [Freeze], [Fear], [True Fear], [Provoke], or [Sheep], debuff from Skills or Artifacts by 5% fearsome-presence](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/fearsome-presence.png)




![Shieldbearer - Increases the value of [Shield], buffs this Champion casts by 5% shieldbearer](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/shieldbearer.png)


![Healing Savior - Increases the amount of healing and the value of [Shield], buffs placed by this Champion by 10% if the target ally has 40% HP or less healing-savior](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/healing-savior.png)



![Merciful Aid - Increases the amount of healing and the value of [Shield], buffs placed by this Champion by 15% if the target ally has [Stun], [Sleep], [Fear], [True Fear], or [Freeze] debuffs merciful-aid](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/merciful-aid.png)



![Lasting Gifts - Has a 30% chance to extend the duration of any buff cast by this Champion by 1 turn.
It will not extend [Block Damage], [Unkillable], or [Revive on Death], buffs. lasting-gifts](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/lasting-gifts.png)

![Sniper - Increases the chances of placing any debuff from Skills or Artifacts by 5%.
It will not increase the chances of placing [Stun], [Sleep], [Freeze], [Fear], [True Fear], [Provoke], or [Petrification], debuffs. sniper](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/sniper.png)
![Master Hexer - Has a 30% chance to extend the duration of any debuff cast by this Champion by 1 turn. It will not extend [Stun], [Sleep], [Freeze], [Provoke], [Fear], [True Fear], [Bomb], or [Petrification], debuffs. master-hexer](https://hellhades.com/wp-content/plugins/rsl-assets/assets/masteries/master-hexer.png)




Dungeon and Boss Blessings
Pythion Relics
Pythion Gear Recommendations
Recommended PVE Stats
SPD, HP%, DEF%, RES
Recommended PVE Artifact Sets
Protection, Stoneskin, Untouchable, Immunity, Regen, Speed, Defiant
Recommended PVP Stats
HP%, RES, SPD, DEF%
Recommended PVP Artifact Sets
Stoneskin, Untouchable, Defiant, Bolster, Guardian, Immortal



