Published On: March 26, 2026
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Best Poison Champions for Dragon Dungeon in Raid Shadow Legends

In this guide, we’ll highlight some of the best Poison champions in Raid: Shadow Legends for tackling the Dragon Dungeon. You’ll learn which champions excel in this role, how the debuff works, and how to build a strong team around Poison to effectively defeat this boss.

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Why poison works well against the dragon

How Poison Damages the Dragon Boss

Poison deals its damage when the Dragon takes a turn, rather than when your champions attack (unless the effect is instantly activated). Each Poison debuff ticks for a percentage of the boss’s MAX HP, either 2.5% or 5% depending on the version, making it highly effective even in longer fights. This allows for strong damage over time as long as the debuffs remain active, even if your team isn’t focused on direct damage. Pairing this with Poison Sensitivity further enhances its effectiveness, increasing Poison damage by 25%.

This damage over time approach is also key during the Dragon’s Inhale phase, where dealing enough damage can prevent the hidden skill, Scorch, from being unlocked. If sufficient damage is dealt during this phase, the skill remains sealed. The same principles apply in Hard Mode, through the interaction between Draconis Gaze and Toxic Incineration while the skill is unlocked.

There are also strategies where a full team carries you to the boss, allowing champions like Bad-el-Kazar, when properly built, to solo the encounter through strong self sustain and Poison application.

Why Poison Is a Reliable Dragon Strategy

Unlike effects such as HP Burn, Poison can be stacked multiple times, allowing you to build up several ticks of damage each time the boss takes a turn. This leads to consistent and reliable damage output, especially if your team lacks strong direct damage dealers. As a result, you can lean more heavily on support champions to keep your team alive while Poison steadily wears the boss down, making it easier to progress through tougher stages.

It’s important, however, to be mindful of the debuff bar, which is limited to 10 slots. Make sure you leave space for key debuffs like Decrease ATK, Decrease DEF, and Weaken if your strategy relies on them, as overfilling the bar with Poison can prevent these crucial effects from being applied.

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What makes a good poison champion for dragon

What makes a strong Poison champion can vary depending on your team setup – whether you’re building around full team synergy or aiming for a solo-style composition. However, at its core, the points below provide a solid foundation for identifying the most effective options:

Consistent Poison Placement

You’ll want to prioritise champions who can place Poison consistently, whether through high activation chances or favourable cooldowns on their skills. Champions with Poison on their A1 or low cooldown abilities are especially valuable, as they ensure frequent application rather than relying on inconsistent or long-cooldown skills that can slow down your run.

It’s also important to remember that the Dragon is a single target encounter, so both AoE and single target Poison abilities hold equal value. What truly matters is how many debuffs a champion can apply, how often they can apply them, and how reliably they can land them.

Survivability and Team Support

You’ll want a team that can safely carry you through the waves, while also supporting your Poisoners and key allies during the boss fight. Defensive effects such as Shields, Strengthen, debuff removal, and Block Debuffs all play a vital role in keeping your team alive, alongside options like Revive and Decrease ATK to further reduce incoming damage.

Some players also opt for Poison Explosion strategies, using champions like Elenaril or Zavia. These setups focus on rapidly clearing waves through Poison detonation, while still maintaining strong Poison damage for the boss itself.

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How to build poison champions for dragon

Accuracy & Speed

Ensuring your team is faster than the boss and has enough Accuracy for the stage you’re tackling is crucial, as resisted debuffs can quickly derail your run. We recommend using the Stages Tool to check the required stat thresholds, allowing you to properly prepare your champions for success.

For example, the Dragon on Stage 25 Normal has 100 Speed and 200 Resistance – so you’ll want to aim for at least 225 Accuracy to reliably land your debuffs. In comparison, Stage 10 of Hard Mode jumps significantly to 250 Speed and 320 Resistance, meaning you should be targeting around 345+ Accuracy to stay consistent.

Utilising effects like Increase Speed and Turn Meter boosts will help you cycle back into your Poison abilities more frequently, while buffs such as Increase ACC can support your team if you’re lacking the required stats as you progress into higher difficulty stages.

Recommended Artifact Sets

Sets that provide Accuracy or Speed are ideal for Poison champions, with options like Speed, Perception, and Feral offering a strong balance of stat boosts to help you land debuffs consistently while taking more turns.

Reflex is another excellent choice, as it can reduce cooldowns and allow your champion to apply Poison more frequently. Regeneration is also valuable for champions who need extra sustain, particularly in solo style setups where a single champion is responsible for handling the boss phase.

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best poison champions for the dragon dungeon

Here we’ve highlighted 10 powerful Poison champions for the Dragon’s Lair Dungeon. While this list isn’t exhaustive, it should give you a clear understanding of what makes these champions so effective. For more options, be sure to check out our Champion Tier List.

DARK KAEL

Dark Kael, one of Nub Raids's Top 10 Epic Champions for Ice Golem.

Dark Kael’s A3 places three 5% Poison debuffs alongside Poison Sensitivity on a short cooldown, allowing for consistent and reliable application across all affinities, as it does not rely on hits. His A1 can then activate existing Poisons, enabling bursts of damage to speed up the run. In addition, he brings Decrease ATK and debuff extension, helping to keep Poisons active for longer and further improving his overall effectiveness.

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Bad-El Kazar

This champion brings a simple yet highly effective kit for the Dragon, and with the right build and stats, is even capable of soloing the boss. His ability to cleanse debuffs, apply Continuous Heals for sustained recovery, and consistently place Poisons creates perfect synergy for the encounter. On top of this, his passive increases the damage allies deal to poisoned targets by 20%, further boosting your team’s overall output.

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Kael

Kael offers a simple and reliable Poison based kit for the Dragon. His A3 attacks four times, with each hit having a chance to place Poison debuffs, providing strong damage over time. His A1 brings additional 2.5% Poisons, while his A2 helps clear waves with AoE damage. Overall, he’s an excellent early game option for progressing through the dungeon.

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Corvis

corvis the corruptor portrait

Corvis is easily one of the best Poison champions for the Dragon. His A3 places four Poison debuffs alongside Poison Sensitivity, increasing the damage from each tick. This, combined with his ability to extend buffs and debuffs, as well as passively reduce damage taken from poisoned enemies, makes him a top-tier choice for this encounter.

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Mithrala Lifebane

Mithrala Lifebane

This champion is a true game changer, and that strength carries into the Dragon as well. Her A1 consistently applies two 5% Poison debuffs, while her A2 provides strong offensive support. Her A3 adds valuable utility through cleansing, alongside placing Shield and Strengthen to keep the team protected, making her both a reliable Poisoner and support option for the encounter.

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Narma

Narma has truly made a comeback following her buffs, and her A3 is the standout ability for Dragon, placing three Poison debuffs alongside Poison Sensitivity. She also passively places Poisons when allies are attacked, reduces damage taken from affected enemies, and brings key debuffs for healing and damage mitigation, along with Poison activation to further boost her overall output.

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Venomage

Venomage-Portrait

Venomage applies Poisons through the A3, placing two alongside Heal Reduction. This Heal Reduction also enables their passive damage reduction, helping your team take less damage. In addition, Venomage brings Decrease ATK and Decrease DEF for strong utility, while the A1 can activate Poisons for burst damage.

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Tomb Lord

Tomb Lord brings one of the strongest Poison abilities in the game, turning a double Poison placement into four when he lands a critical hit. This makes him exceptional for both Poison Explosion strategies in wave clearing and for stacking damage against the boss. On top of this, he also provides Decrease ATK and Decrease DEF, adding valuable utility alongside his high Poison output.

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Xenomorph

Xenomorph Portrait

Xenomorph excels not only in raw damage, using his Infest ability to deal splash damage, but also in his ability to stack Poisons efficiently. His A1 can place three Poison debuffs on a target when it lands as a critical hit, allowing for rapid buildup of damage over time. These Poisons also enhance the effectiveness of his A3, increasing his overall damage output and helping bring down the boss more quickly.

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Teodor

Teodor Portrait

Teodor is unique in the way he combines multiple roles into a single kit, placing Poisons, Poison Sensitivity, and Increase Speed all within one skill. On top of this, his A3 can activate ticks of Poison and HP Burn debuffs, allowing for immediate burst damage. This versatility makes him an exceptional all-in-one option for Dragon teams, covering damage, support, and debuff utility.

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Champions that support poison strategies

Dragon 20

Poison Sensitivity Champions

Champions that bring Poison Sensitivity aren’t essential to a Poison-focused strategy, but they are a strong complement if you can include them. This debuff increases Poison damage by 25%, meaning a 5% Poison will instead deal 6.25% of the target’s MAX HP, boosting your overall damage output.

Ideally, you’ll gain access to this effect through your existing Poison champions, such as Frozen Banshee, Teodor, or Corvis, allowing you to combine multiple roles within a single champion for greater team efficiency.

Debuff Extension Champions

Over longer fights, extending the duration of your debuffs is valuable, as it allows you to gain additional Poison ticks without needing to constantly reapply them. This is especially useful for champions with longer cooldowns, helping to maintain uptime while their skills cycle back around. It also ensures your Poison stacks remain active for longer, preventing them from falling off and keeping your damage consistent throughout the fight.

Wave Clear Champions

Your wave clearers ensure a smooth and efficient path to the boss. This can include crowd control champions who lock down enemies, strong damage dealers like Staltus who also offer boss utility, or specialists like Seer and Poison Explosion teams that can instantly wipe waves. Ideally, these champions should also bring some form of utility into the boss fight, such as support, cleansing, or additional damage.

Support Champions

Support champions play a key role in enabling your team’s performance. Increase Speed and Turn Meter boosts help you outpace the boss and cycle skills more effectively, while debuffs such as Decrease DEF and Weaken significantly increase your team’s damage output to bring the Dragon down faster. Just be mindful of the debuff bar limit if you’re heavily stacking Poisons, ensuring there’s still space for these crucial effects.

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Tips for beating the dragon with poisons

To defeat the Dragon with poisons, focus on building a team that can reliably stack Poison debuffs while staying alive through the waves and boss phase. Poison is your primary source of damage, continuing to tick each time the Dragon takes a turn, so champions who can apply it consistently – ideally on low cooldowns or A1s are key.

Pair this with Poison Sensitivity and debuff extension where possible to maximise uptime and damage. Support your Poisoners with defensive effects like Shields, Heals, cleansing, and Decrease ATK to survive, while ensuring your team has enough Speed and Accuracy to avoid being outpaced or resisted. Be mindful of the 10-debuff limit so you can still place important effects like Decrease DEF and Weaken, and consider strategies like Poison Explosion for faster wave clears or solo-style sustain setups for the boss.

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LET US KNOW IN THE COMMENTS WHO YOUR TOP POISON CHAMPIONS ARE TO DEFEAT THE DRAGON!

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